The final say is with the developer and, sadly, CS6/Acrobat Pro XI are unsupported 'old' applications these days.

Won't be moving OS until I have to! What makes it worse is that I checked with Apple that Big Sur would run ALL 64-bit applications, but this is NOT the case. I can confirm that Bridge CS6 works (though I also seem to be able to get Bridge CC free with a non-subscription Adobe ID account.) Dreamweaver CS6 works, but is sluggish for me. This includes Distiller, mentioned in another answer as unworking. Just happy to be back in Mojave with everything working again. As of July 2019 (Mojave 10.14.5), CS6 suite works for me. I had the same problem with Acrobat Pro XI but if and when I have to move to Big Sur (or later), Readdle's 64-bit PDF Expert for Mac seems to do everything I need. Adobe Illustrator Cs6 is available in 32-bit and 64-bit versions for both Mac and Windows operating systems. examines Macintosh OS X Lion and Windows 7 operating systems, as well the Big 3 digital design programs used in the graphics industry today: Adobe Illustrator CS6, Adobe Photoshop CS6, and Adobe InDesign CS6. I am exploring whether I can use Skylum Luminar, Affinity, or DxO instead. As an amateur Photographer (and being retired) I can't justify the CC subscription when CS6 does all, and more, than I need. I had a real problem reverting to Mojave from TimeMachine but got there in the end with telephone support one Sunday from Apple in Dublin. UPDATE Mac OS X v10.8 Mountain Lion is out and there are no known issues reported with Adobe CS applications. I guess there are 32-bit parts in the Application Libraries or elsewhere. Looking in 'About this Mac' shows Adobe Photoshop CS6 as 64-bit.

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